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rAAV Manufacturing: The Challenges of Soft Sensing during Upstream Processing

Recombinant adeno-associated virus (rAAV) is the most effective viral vector technology for directly translating the genomic revolution into medicinal therapies. However, the manufacturing of rAAV viral vectors remains challenging in the upstream processing with low rAAV yield in large-scale product...

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Detalles Bibliográficos
Autores principales: Iglesias, Cristovão Freitas, Ristovski, Milica, Bolic, Miodrag, Cuperlovic-Culf, Miroslava
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951952/
https://www.ncbi.nlm.nih.gov/pubmed/36829723
http://dx.doi.org/10.3390/bioengineering10020229