Influence of 2-Nitroimidazoles in the Response of FaDu Cells to Ionizing Radiation and Hypoxia/Reoxygenation Stress

Cellular adaptations to hypoxia promote resistance to ionizing radiation (IR). This presents a challenge for treatment of head and neck cancer (HNC) that relies heavily on radiotherapy. Standard radiosensitizers often fail to reach diffusion-restricted hypoxic cells, whereas nitroimidazoles (NIs) [s...

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Detalles Bibliográficos
Autores principales: Rashed, Faisal Bin, Kate, Wisdom Deebeke, Fanta, Mesfin, Wiebe, Leonard Irving, Kumar, Piyush, Weinfeld, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951954/
https://www.ncbi.nlm.nih.gov/pubmed/36829948
http://dx.doi.org/10.3390/antiox12020389

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951954/
https://www.ncbi.nlm.nih.gov/pubmed/36829948
http://dx.doi.org/10.3390/antiox12020389

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