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Influence of 2-Nitroimidazoles in the Response of FaDu Cells to Ionizing Radiation and Hypoxia/Reoxygenation Stress
Cellular adaptations to hypoxia promote resistance to ionizing radiation (IR). This presents a challenge for treatment of head and neck cancer (HNC) that relies heavily on radiotherapy. Standard radiosensitizers often fail to reach diffusion-restricted hypoxic cells, whereas nitroimidazoles (NIs) [s...
Autores principales: | Rashed, Faisal Bin, Kate, Wisdom Deebeke, Fanta, Mesfin, Wiebe, Leonard Irving, Kumar, Piyush, Weinfeld, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951954/ https://www.ncbi.nlm.nih.gov/pubmed/36829948 http://dx.doi.org/10.3390/antiox12020389 |
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