Fragment-Based Lead Discovery Strategies in Antimicrobial Drug Discovery

Fragment-based lead discovery (FBLD) is a powerful application for developing ligands as modulators of disease targets. This approach strategy involves identification of interactions between low-molecular weight compounds (100–300 Da) and their putative targets, often with low affinity (K(D) ~0.1–1...

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Detalles Bibliográficos
Autores principales: Konaklieva, Monika I., Plotkin, Balbina J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951956/
https://www.ncbi.nlm.nih.gov/pubmed/36830226
http://dx.doi.org/10.3390/antibiotics12020315

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951956/
https://www.ncbi.nlm.nih.gov/pubmed/36830226
http://dx.doi.org/10.3390/antibiotics12020315

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