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Characterization and Preliminary In Vitro Antioxidant Activity of a New Multidrug Formulation Based on the Co-Encapsulation of Rutin and the α-Acylamino-β-Lactone NAAA Inhibitor URB894 within PLGA Nanoparticles

A biodegradable and biocompatible polymeric matrix made up of poly(d,l-lactide-co-glycolide) (PLGA) was used for the simultaneous delivery of rutin and the (S)-N-(2-oxo-3-oxetanyl)biphenyl-4-carboxamide derivative (URB894). The goal was to exploit the well-known radical scavenging properties of ruti...

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Detalles Bibliográficos
Autores principales: Gagliardi, Agnese, Voci, Silvia, Ambrosio, Nicola, Fresta, Massimo, Duranti, Andrea, Cosco, Donato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951992/
https://www.ncbi.nlm.nih.gov/pubmed/36829864
http://dx.doi.org/10.3390/antiox12020305