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Failure to Thrive: Impaired BDNF Transport along the Cortical–Striatal Axis in Mouse Q140 Neurons of Huntington’s Disease

SIMPLE SUMMARY: The brain-derived neurotrophic factor (BDNF) is implicated in the function and survival of striatal neurons. Deficits in neurotrophic support by BDNF have been hypothesized to contribute to the neurodegeneration of striatal neurons in Huntington’s disease (HD). This article outlines...

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Detalles Bibliográficos
Autores principales: Maloney, Michael T., Wang, Wei, Bhowmick, Sumana, Millan, Ivan, Kapur, Mridu, Herrera, Nicolas, Frost, Everett, Zhang, Elena Y., Song, Scott, Wang, Melissa, Park, Amelia Bora, Yao, Annabelle Y., Yang, Yanmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952218/
https://www.ncbi.nlm.nih.gov/pubmed/36829435
http://dx.doi.org/10.3390/biology12020157