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Inside the Mechanism of Action of Three Pyrazole Derivatives in Human Platelets and Endothelial Cells
In the effort to obtain multitarget compound interfering with inflammation, oxidative stress, and tumorigenesis, we synthesized a small library of pyrazole compounds, selecting 4a, 4f, and 4g as the most noteworthy being IC(50) against platelet ROS production induced by thrombin of about 10 µM. The...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952262/ https://www.ncbi.nlm.nih.gov/pubmed/36829775 http://dx.doi.org/10.3390/antiox12020216 |