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Mitochondrial Peroxiredoxin 3 Is Rapidly Oxidized and Hyperoxidized by Fatty Acid Hydroperoxides

Human peroxiredoxin 3 (HsPrx3) is a thiol-based peroxidase responsible for the reduction of most hydrogen peroxide and peroxynitrite formed in mitochondria. Mitochondrial disfunction can lead to membrane lipoperoxidation, resulting in the formation of lipid-bound fatty acid hydroperoxides ((L)FA-OOH...

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Detalles Bibliográficos
Autores principales: Cardozo, Giuliana, Mastrogiovanni, Mauricio, Zeida, Ari, Viera, Nicolás, Radi, Rafael, Reyes, Aníbal M., Trujillo, Madia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952270/
https://www.ncbi.nlm.nih.gov/pubmed/36829967
http://dx.doi.org/10.3390/antiox12020408