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CHIR99021 Maintenance of the Cell Stemness by Regulating Cellular Iron Metabolism

CHIR99021 is an aminopyrimidine derivative, which can efficiently inhibit the activity of glycogen synthesis kinase 3α (GSK-3α) and GSK-3β. As an essential component of stem cell culture medium, it plays an important role in maintaining cell stemness. However, the mechanism of its role is not fully...

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Detalles Bibliográficos
Autores principales: Han, Yingying, He, Yong, Jin, Xiaofang, Xie, Jiayi, Yu, Peng, Gao, Guofen, Chang, Shiyang, Zhang, Jianhua, Chang, Yan-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952287/
https://www.ncbi.nlm.nih.gov/pubmed/36829936
http://dx.doi.org/10.3390/antiox12020377