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Structure, Activation, and Regulation of NOX2: At the Crossroad between the Innate Immunity and Oxidative Stress-Mediated Pathologies

Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) is a multisubunit enzyme complex that participates in the generation of superoxide or hydrogen peroxide (H(2)O(2)) and plays a key role in several biological functions. Among seven known NOX isoforms, NOX2 was the first identified in...

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Detalles Bibliográficos
Autores principales: Nocella, Cristina, D’Amico, Alessandra, Cammisotto, Vittoria, Bartimoccia, Simona, Castellani, Valentina, Loffredo, Lorenzo, Marini, Leonardo, Ferrara, Giulia, Testa, Matteo, Motta, Giulio, Benazzi, Beatrice, Zara, Fabio, Frati, Giacomo, Sciarretta, Sebastiano, Pignatelli, Pasquale, Violi, Francesco, Carnevale, Roberto, Group, Smile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952346/
https://www.ncbi.nlm.nih.gov/pubmed/36829988
http://dx.doi.org/10.3390/antiox12020429