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A Validated UHPLC–MS/MS Method to Quantify Eight Antibiotics in Quantitative Dried Blood Spots in Support of Pharmacokinetic Studies in Neonates

Objectives: Conduction of pharmacokinetic (PK) study in pediatric patients is challenging due to blood sampling limits. The dried blood spots (DBS) method represents a potential matrix for microsampling in support of PK studies in children. Herein, we used the Capitainer(®) qDBS device to develop a...

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Detalles Bibliográficos
Autores principales: Liu, Qian, Liu, Lanyu, Yuan, Yu, Xie, Feifan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952362/
https://www.ncbi.nlm.nih.gov/pubmed/36830110
http://dx.doi.org/10.3390/antibiotics12020199