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Therapeutic Potential of an Azithromycin-Colistin Combination against XDR K. pneumoniae in a 3D Collagen-Based In Vitro Wound Model of a Biofilm Infection

A therapeutic combination of azithromycin (AZM) and colistin methanesulfonate (CMS) was shown to be effective against both non-PDR and PDR Klebsiella pneumoniae biofilms in vitro. These anti-biofilm effects, however, may not correlate with effects observed in standard plate assays, nor will they rep...

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Detalles Bibliográficos
Autores principales: Moshynets, Olena V., Baranovskyi, Taras P., Iungin, Olga S., Krikunov, Alexey A., Potochilova, Viktoria V., Rudnieva, Kateryna L., Potters, Geert, Pokholenko, Ianina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952533/
https://www.ncbi.nlm.nih.gov/pubmed/36830203
http://dx.doi.org/10.3390/antibiotics12020293