Hypochlorous Acid and Chloramines Induce Specific Fragmentation and Cross-Linking of the G1-IGD-G2 Domains of Recombinant Human Aggrecan, and Inhibit ADAMTS1 Activity

Atherosclerosis is a chronic inflammatory disease and a leading cause of mortality. It is characterized by arterial wall plaques that contain high levels of cholesterol and other lipids and activated leukocytes covered by a fibrous cap of extracellular matrix (ECM). The ECM undergoes remodelling dur...

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Detalles Bibliográficos
Autores principales: Wang, Yihe, Hammer, Astrid, Hoefler, Gerald, Malle, Ernst, Hawkins, Clare L., Chuang, Christine Y., Davies, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952545/
https://www.ncbi.nlm.nih.gov/pubmed/36829979
http://dx.doi.org/10.3390/antiox12020420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952545/
https://www.ncbi.nlm.nih.gov/pubmed/36829979
http://dx.doi.org/10.3390/antiox12020420

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