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Zinc Protoporphyrin-9 Potentiates the Anticancer Activity of Dihydroartemisinin

Besides the clinically proven superior antimalarial activity, artemisinins (ARTs) are also associated with anticancer properties, albeit at much lower potency. Iron and heme have been proposed as possible activators of ARTs against cancer cells. Here we show that zinc protoporphyrin-9 (ZnPPIX), a he...

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Detalles Bibliográficos
Autores principales: Zhang, Yu, Zhang, Xu, Zhou, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952556/
https://www.ncbi.nlm.nih.gov/pubmed/36829809
http://dx.doi.org/10.3390/antiox12020250