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α-Synuclein Toxicity in Drosophila melanogaster Is Enhanced by the Presence of Iron: Implications for Parkinson’s Disease

Parkinson’s disease (PD) is the second most common neurodegenerative disorder, characterized by the preferential loss of dopaminergic neurons and by the accumulation of intracellular inclusions mainly composed of α-synuclein (α-Syn). While the etiopathogenesis of the disorder is still elusive, recen...

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Detalles Bibliográficos
Autores principales: Agostini, Francesco, Bubacco, Luigi, Chakrabarti, Sasanka, Bisaglia, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952566/
https://www.ncbi.nlm.nih.gov/pubmed/36829820
http://dx.doi.org/10.3390/antiox12020261