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DMF-Activated Nrf2 Ameliorates Palmitic Acid Toxicity While Potentiates Ferroptosis Mediated Cell Death: Protective Role of the NO-Donor S-Nitroso-N-Acetylcysteine

Nonalcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease that can develop into an aggressive form called nonalcoholic steatohepatitis (NASH), which ultimately progresses to cirrhosis, hepatocellular carcinoma (HCC), and end-stage liver failure. Currently, the deterioratio...

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Detalles Bibliográficos
Autores principales: Abu-Halaka, Diana, Shpaizer, Adi, Zeigerman, Haim, Kanner, Joseph, Tirosh, Oren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952671/
https://www.ncbi.nlm.nih.gov/pubmed/36830070
http://dx.doi.org/10.3390/antiox12020512