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Mitochondria-Targeted Curcumin: A Potent Antibacterial Agent against Methicillin-Resistant Staphylococcus aureus with a Possible Intracellular ROS Accumulation as the Mechanism of Action

Mitocurcumin (a triphenylphosphonium curcumin derivative) was previously reported as a selective antitumoral compound on different cellular lines, as well as a potent bactericidal candidate. In this study, the same compound showed strong antimicrobial efficacy against different strains of methicilli...

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Detalles Bibliográficos
Autores principales: Leferman, Carmen-Ecaterina, Stoica, Laura, Stoica, Bogdan Alexandru, Ciubotaru, Alin Dumitru, Badescu, Aida Corina, Bogdanici, Camelia-Margareta, Neagu, Tiberiu Paul, Ghiciuc, Cristina-Mihaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952693/
https://www.ncbi.nlm.nih.gov/pubmed/36830311
http://dx.doi.org/10.3390/antibiotics12020401