IGF-1 Controls Metabolic Homeostasis and Survival in HEI-OC1 Auditory Cells through AKT and mTOR Signaling

Insulin-like growth factor 1 (IGF-1) is a trophic factor for the nervous system where it exerts pleiotropic effects, including the regulation of metabolic homeostasis. IGF-1 deficiency induces morphological alterations in the cochlea, apoptosis and hearing loss. While multiple studies have addressed...

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Detalles Bibliográficos
Autores principales: García-Mato, Ángela, Cervantes, Blanca, Rodríguez-de la Rosa, Lourdes, Varela-Nieto, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952701/
https://www.ncbi.nlm.nih.gov/pubmed/36829792
http://dx.doi.org/10.3390/antiox12020233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952701/
https://www.ncbi.nlm.nih.gov/pubmed/36829792
http://dx.doi.org/10.3390/antiox12020233

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