Vancomycin-Loaded, Nanohydroxyapatite-Based Scaffold for Osteomyelitis Treatment: In Vivo Rabbit Toxicological Tests and In Vivo Efficacy Tests in a Sheep Model

The treatment for osteomyelitis consists of surgical debridement, filling of the dead space, soft tissue coverage, and intravenous administration of antimicrobial (AM) agents for long periods. Biomaterials for local delivery of AM agents, while providing controllable antibiotic release rates and sim...

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Detalles Bibliográficos
Autores principales: Alegrete, Nuno, Sousa, Susana R., Padrão, Tatiana, Carvalho, Ângela, Lucas, Raquel, Canadas, Raphael F., Lavrador, Catarina, Alexandre, Nuno, Gärtner, Fátima, Monteiro, Fernando J., Gutierres, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952702/
https://www.ncbi.nlm.nih.gov/pubmed/36829700
http://dx.doi.org/10.3390/bioengineering10020206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952702/
https://www.ncbi.nlm.nih.gov/pubmed/36829700
http://dx.doi.org/10.3390/bioengineering10020206

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