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Adequacy of the 10 mg/kg Daily Dose of Antituberculosis Drug Isoniazid in Infants under 6 Months of Age

In 2010, the WHO recommended an increase in the daily doses of first-line anti-tuberculosis medicines in children. We aim to characterize the pharmacokinetics of the once-daily isoniazid (INH) dose at 10 mg/kg of body weight in infants <6 months of age. We performed a multicenter pharmacokinetic...

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Detalles Bibliográficos
Autores principales: López-Ramos, Maria Goretti, Vinent, Joan, Aarnoutse, Rob, Colbers, Angela, Velasco-Arnaiz, Eneritz, Martorell, Loreto, Falcón-Neyra, Lola, Neth, Olaf, Prieto, Luis, Guillén, Sara, Baquero-Artigao, Fernando, Méndez-Echevarría, Ana, Gómez-Pastrana, David, Jiménez, Ana Belén, Lahoz, Rebeca, Ramos-Amador, José Tomás, Soriano-Arandes, Antoni, Santiago, Begoña, Farré, Rosa, Fortuny, Clàudia, Soy, Dolors, Noguera-Julian, Antoni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952805/
https://www.ncbi.nlm.nih.gov/pubmed/36830184
http://dx.doi.org/10.3390/antibiotics12020272