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Inhibition of Mitochondrial Uncoupling Proteins Arrests Human Spermatozoa Motility without Compromising Viability

Mitochondrial uncoupling proteins (UCPs) are central in the regulation of mitochondrial activity and reactive oxygen species (ROS) production. High oxidative stress is a major cause of male infertility; however, UCPs expression and function in human spermatozoa are still unknown. Herein, we aimed to...

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Detalles Bibliográficos
Autores principales: Carrageta, David F., Freire-Brito, Laís, Guerra-Carvalho, Bárbara, Ribeiro, João C., Monteiro, Bruno S., Barros, Alberto, Oliveira, Pedro F., Monteiro, Mariana P., Alves, Marco G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952840/
https://www.ncbi.nlm.nih.gov/pubmed/36829970
http://dx.doi.org/10.3390/antiox12020409