The Anti-Aging Hormone Klotho Promotes Retinal Pigment Epithelium Cell Viability and Metabolism by Activating the AMPK/PGC-1α Pathway

Initially discovered by Makuto Kuro-o in 1997, Klotho is a putative aging-suppressor gene when overexpressed and accelerates aging when deleted in mice. Previously, we showed that α-Klotho regulates retinal pigment epithelium (RPE) functions and protects against oxidative stress. However, the mechan...

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Detalles Bibliográficos
Autores principales: Zhou, Shuyan, Hum, Jacob, Taskintuna, Kaan, Olaya, Stephanie, Steinman, Jeremy, Ma, Junfeng, Golestaneh, Nady
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952846/
https://www.ncbi.nlm.nih.gov/pubmed/36829944
http://dx.doi.org/10.3390/antiox12020385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952846/
https://www.ncbi.nlm.nih.gov/pubmed/36829944
http://dx.doi.org/10.3390/antiox12020385

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