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Selective Destabilization of Transcripts by mRNA Decapping Regulates Oocyte Maturation and Innate Immunity Gene Expression during Ageing in C. elegans

SIMPLE SUMMARY: In eukaryotes, the elimination of the protective cap from 5′ end of messenger RNA (mRNA) by the decapping complex is an important mechanism of mRNA decay and translation, affecting several cellular processes. In the nematode C. elegans, perturbations in decapping activity slow develo...

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Detalles Bibliográficos
Autores principales: Borbolis, Fivos, Ranti, Dimitra, Papadopoulou, Maria-Despina, Dimopoulou, Sofia, Malatras, Apostolos, Michalopoulos, Ioannis, Syntichaki, Popi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952881/
https://www.ncbi.nlm.nih.gov/pubmed/36829450
http://dx.doi.org/10.3390/biology12020171