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A New Insight into MYC Action: Control of RNA Polymerase II Methylation and Transcription Termination

MYC oncoprotein deregulation is a common catastrophic event in human cancer and limiting its activity restrains tumor development and maintenance, as clearly shown via Omomyc, an MYC-interfering 90 amino acid mini-protein. MYC is a multifunctional transcription factor that regulates many aspects of...

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Detalles Bibliográficos
Autores principales: Scagnoli, Fiorella, Palma, Alessandro, Favia, Annarita, Scuoppo, Claudio, Illi, Barbara, Nasi, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952900/
https://www.ncbi.nlm.nih.gov/pubmed/36830948
http://dx.doi.org/10.3390/biomedicines11020412