Melatonin Activates Anti-Inflammatory Features in Microglia in a Multicellular Context: Evidence from Organotypic Brain Slices and HMC3 Cells

Melatonin (MEL) is a neurohormone endowed with neuroprotective activity, exerted both directly on neuronal cells and indirectly through modulation of responsive glial cells. In particular, MEL’s effects on microglia are receptor-mediated and in part dependent on SIRT1 activation. In the present stud...

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Detalles Bibliográficos
Autores principales: Merlo, Sara, Caruso, Grazia Ilaria, Korde, Dhwani Sunil, Khodorovska, Alla, Humpel, Christian, Sortino, Maria Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952958/
https://www.ncbi.nlm.nih.gov/pubmed/36830742
http://dx.doi.org/10.3390/biom13020373

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952958/
https://www.ncbi.nlm.nih.gov/pubmed/36830742
http://dx.doi.org/10.3390/biom13020373

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