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Targeting Periostin Expression Makes Pancreatic Cancer Spheroids More Vulnerable to Natural Killer Cells

Pancreatic cancer (PaCa) characteristically has a dense tumor microenvironment, which results in poor patient prognosis. Pancreatic stellate cells (PSCs) are the most abundant cells in the PaCa microenvironment and the principal source of collagen. Periostin, a matricellular protein, is produced spe...

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Detalles Bibliográficos
Autores principales: Karakas, Didem, Erkisa, Merve, Akar, Remzi Okan, Akman, Gizem, Senol, Ezgi Yudum, Ulukaya, Engin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952976/
https://www.ncbi.nlm.nih.gov/pubmed/36830807
http://dx.doi.org/10.3390/biomedicines11020270