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Targeting Periostin Expression Makes Pancreatic Cancer Spheroids More Vulnerable to Natural Killer Cells
Pancreatic cancer (PaCa) characteristically has a dense tumor microenvironment, which results in poor patient prognosis. Pancreatic stellate cells (PSCs) are the most abundant cells in the PaCa microenvironment and the principal source of collagen. Periostin, a matricellular protein, is produced spe...
Autores principales: | Karakas, Didem, Erkisa, Merve, Akar, Remzi Okan, Akman, Gizem, Senol, Ezgi Yudum, Ulukaya, Engin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952976/ https://www.ncbi.nlm.nih.gov/pubmed/36830807 http://dx.doi.org/10.3390/biomedicines11020270 |
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