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Molecular Characteristics of Toxicity of Acrolein Produced from Spermine

Acrolein (CH(2)=CH-CHO), an unsaturated aldehyde produced from spermine, is one of the major contributors to oxidative stress. Acrolein has been found to be more toxic than reactive oxygen species (H(2)O(2) and •OH), and it can be easily conjugated with proteins, bringing about changes in nature of...

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Detalles Bibliográficos
Autores principales: Kashiwagi, Keiko, Igarashi, Kazuei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952977/
https://www.ncbi.nlm.nih.gov/pubmed/36830667
http://dx.doi.org/10.3390/biom13020298