Computational Approaches to the Rational Design of Tubulin-Targeting Agents

Microtubules are highly dynamic polymers of α,β-tubulin dimers which play an essential role in numerous cellular processes such as cell proliferation and intracellular transport, making them an attractive target for cancer and neurodegeneration research. To date, a large number of known tubulin bind...

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Detalles Bibliográficos
Autores principales: Pérez-Peña, Helena, Abel, Anne-Catherine, Shevelev, Maxim, Prota, Andrea E., Pieraccini, Stefano, Horvath, Dragos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952983/
https://www.ncbi.nlm.nih.gov/pubmed/36830654
http://dx.doi.org/10.3390/biom13020285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952983/
https://www.ncbi.nlm.nih.gov/pubmed/36830654
http://dx.doi.org/10.3390/biom13020285

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