A Combined in Silico and Structural Study Opens New Perspectives on Aliphatic Sulfonamides, a Still Poorly Investigated Class of CA Inhibitors

SIMPLE SUMMARY: Carbonic anhydrases are a family of enzymes that catalyze an essential physiological reaction for living organisms: the reversible conversion of CO(2) to bicarbonate ion. In humans, these enzymes impact many physiological and pathological processes including respiration, pH and CO(2)...

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Detalles Bibliográficos
Autores principales: Langella, Emma, Esposito, Davide, Monti, Simona Maria, Supuran, Claudiu T., De Simone, Giuseppina, Alterio, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953064/
https://www.ncbi.nlm.nih.gov/pubmed/36829558
http://dx.doi.org/10.3390/biology12020281

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953064/
https://www.ncbi.nlm.nih.gov/pubmed/36829558
http://dx.doi.org/10.3390/biology12020281

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