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A Combined in Silico and Structural Study Opens New Perspectives on Aliphatic Sulfonamides, a Still Poorly Investigated Class of CA Inhibitors
SIMPLE SUMMARY: Carbonic anhydrases are a family of enzymes that catalyze an essential physiological reaction for living organisms: the reversible conversion of CO(2) to bicarbonate ion. In humans, these enzymes impact many physiological and pathological processes including respiration, pH and CO(2)...
Autores principales: | Langella, Emma, Esposito, Davide, Monti, Simona Maria, Supuran, Claudiu T., De Simone, Giuseppina, Alterio, Vincenzo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953064/ https://www.ncbi.nlm.nih.gov/pubmed/36829558 http://dx.doi.org/10.3390/biology12020281 |
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