Dysregulation of Mycobacterium marinum ESX-5 Secretion by Novel 1,2,4-oxadiazoles

The ESX-5 secretion system is essential for the viability and virulence of slow-growing pathogenic mycobacterial species. In this study, we identified a 1,2,4-oxadiazole derivative as a putative effector of the ESX-5 secretion system. We confirmed that this 1,2,4-oxadiazole and several newly synthes...

Descripción completa

Detalles Bibliográficos
Autores principales: Ho, Vien Q. T., Rong, Mark K., Habjan, Eva, Bommer, Samantha D., Pham, Thang V., Piersma, Sander R., Bitter, Wilbert, Ruijter, Eelco, Speer, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953084/
https://www.ncbi.nlm.nih.gov/pubmed/36830581
http://dx.doi.org/10.3390/biom13020211

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953084/
https://www.ncbi.nlm.nih.gov/pubmed/36830581
http://dx.doi.org/10.3390/biom13020211

Ejemplares similares