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Short-Term UVB Irradiation Leads to Persistent DNA Damage in Limbal Epithelial Stem Cells, Partially Reversed by DNA Repairing Enzymes

SIMPLE SUMMARY: Ultraviolet light from the sun causes DNA damage and is a major exogenous genotoxin, particularly affecting the skin and eyes of humans. UV-induced lesions are repaired by complex DNA repair mechanisms that sometimes fail, leading to burns or cancers. Here, we probe the potential of...

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Detalles Bibliográficos
Autores principales: Volatier, Thomas, Schumacher, Björn, Meshko, Berbang, Hadrian, Karina, Cursiefen, Claus, Notara, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953128/
https://www.ncbi.nlm.nih.gov/pubmed/36829542
http://dx.doi.org/10.3390/biology12020265