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Identification of Activated Cdc42-Associated Kinase Inhibitors as Potential Anticancer Agents Using Pharmacoinformatic Approaches

Background: Activated Cdc42-associated kinase (ACK1) is essential for numerous cellular functions, such as growth, proliferation, and migration. ACK1 signaling occurs through multiple receptor tyrosine kinases; therefore, its inhibition can provide effective antiproliferative effects against multipl...

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Detalles Bibliográficos
Autores principales: Kumar, Vikas, Kumar, Raj, Parate, Shraddha, Danishuddin, Lee, Gihwan, Kwon, Moonhyuk, Jeong, Seong-Hee, Ro, Hyeon-Su, Lee, Keun Woo, Kim, Seon-Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953130/
https://www.ncbi.nlm.nih.gov/pubmed/36830587
http://dx.doi.org/10.3390/biom13020217