Liver X Receptor Inverse Agonist GAC0001E5 Impedes Glutaminolysis and Disrupts Redox Homeostasis in Breast Cancer Cells

Liver X receptors (LXRs) are members of the nuclear receptor family of ligand-dependent transcription factors which regulate the expression of lipid and cholesterol metabolism genes. Moreover, LXRs and their ligands have been shown to inhibit tumor growth in a variety of cancers. We have previously...

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Detalles Bibliográficos
Autores principales: Premaratne, Asitha, Ho, Charles, Basu, Shinjini, Khan, Ashfia Fatima, Bawa-Khalfe, Tasneem, Lin, Chin-Yo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953168/
https://www.ncbi.nlm.nih.gov/pubmed/36830714
http://dx.doi.org/10.3390/biom13020345

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953168/
https://www.ncbi.nlm.nih.gov/pubmed/36830714
http://dx.doi.org/10.3390/biom13020345

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