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Liver X Receptor Inverse Agonist GAC0001E5 Impedes Glutaminolysis and Disrupts Redox Homeostasis in Breast Cancer Cells
Liver X receptors (LXRs) are members of the nuclear receptor family of ligand-dependent transcription factors which regulate the expression of lipid and cholesterol metabolism genes. Moreover, LXRs and their ligands have been shown to inhibit tumor growth in a variety of cancers. We have previously...
Autores principales: | Premaratne, Asitha, Ho, Charles, Basu, Shinjini, Khan, Ashfia Fatima, Bawa-Khalfe, Tasneem, Lin, Chin-Yo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953168/ https://www.ncbi.nlm.nih.gov/pubmed/36830714 http://dx.doi.org/10.3390/biom13020345 |
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