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Mesenchymal Stem Cells Genetically Modified by Lentivirus-Express Soluble TRAIL and Interleukin-12 Inhibit Growth and Reduced Metastasis-Relate Changes in Lymphoma Mice Model

Background: Cancer treatment has many side effects; therefore, more efficient treatments are needed. Mesenchymal stem cells (MSC) have immunoregulatory properties, tumor site migration and can be genetically modified. Some proteins, such as soluble TRAIL (sTRAIL) and interleukin-12 (IL-12), have sho...

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Detalles Bibliográficos
Autores principales: Quiroz-Reyes, Adriana G., Gonzalez-Villarreal, Carlos A., Limon-Flores, Alberto Y., Delgado-Gonzalez, Paulina, Martinez-Rodriguez, Herminia G., Said-Fernandez, Salvador L., Soto-Dominguez, Adolfo, Rivas-Estilla, Ana M., Islas, Jose F., Molina-De la Garza, Juan F., Garza-Treviño, Elsa N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953195/
https://www.ncbi.nlm.nih.gov/pubmed/36831131
http://dx.doi.org/10.3390/biomedicines11020595