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Design and Prediction of Aptamers Assisted by In Silico Methods

An aptamer is a single-stranded DNA or RNA that binds to a specific target with high binding affinity. Aptamers are developed through the process of systematic evolution of ligands by exponential enrichment (SELEX), which is repeated to increase the binding power and specificity. However, the SELEX...

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Detalles Bibliográficos
Autores principales: Lee, Su Jin, Cho, Junmin, Lee, Byung-Hoon, Hwang, Donghwan, Park, Jee-Woong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953197/
https://www.ncbi.nlm.nih.gov/pubmed/36830893
http://dx.doi.org/10.3390/biomedicines11020356