Mutual Influence of Human Cytochrome P450 Enzymes and UDP-Glucuronosyltransferases on Their Respective Activities in Recombinant Fission Yeast

Cytochromes P450 (CYPs) and UDP-glucuronosyltransferases (UGTs) are the most important human drug metabolizing enzymes, but their mutual interactions are poorly understood. In this study, we recombinantly co-expressed of each one of the 19 human members of the UGT families 1 and 2 with either CYP2C9...

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Detalles Bibliográficos
Autores principales: Sharma, Sangeeta Shrestha, Sharma, Shishir, Zhao, Jie, Bureik, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953201/
https://www.ncbi.nlm.nih.gov/pubmed/36830817
http://dx.doi.org/10.3390/biomedicines11020281

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953201/
https://www.ncbi.nlm.nih.gov/pubmed/36830817
http://dx.doi.org/10.3390/biomedicines11020281

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