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Search Strategy Analysis of 5xFAD Alzheimer Mice in the Morris Water Maze Reveals Sex- and Age-Specific Spatial Navigation Deficits

Spatial disorientation and navigational impairments are not only some of the first memory deficits in Alzheimer’s disease, but are also very disease-specific. In rodents, the Morris Water Maze is used to investigate spatial navigation and memory. Here, we examined the spatial memory in the commonly...

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Detalles Bibliográficos
Autores principales: Sánchez, Carolina Quintanilla, Schmitt, Franziska W., Curdt, Nadine, Westhoff, Anna Celine, Bänfer, Irina Wanda Helene, Bayer, Thomas A., Bouter, Yvonne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953202/
https://www.ncbi.nlm.nih.gov/pubmed/36831135
http://dx.doi.org/10.3390/biomedicines11020599