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GABA-A Alpha 2/3 but Not Alpha 1 Receptor Subunit Ligand Inhibits Harmaline and Pimozide-Induced Tremor in Rats

Treatment of tremors, such as in essential tremor (ET) and Parkinson’s disease (PD) is mostly ineffective. Exact tremor pathomechanisms are unknown and relevant animal models are missing. GABA-A receptor is a target for tremorolytic medications, but current non-selective drugs produce side effects a...

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Detalles Bibliográficos
Autores principales: Kosmowska, Barbara, Paleczna, Martyna, Biała, Dominika, Kadłuczka, Justyna, Wardas, Jadwiga, Witkin, Jeffrey M., Cook, James M., Sharmin, Dishary, Marcinkowska, Monika, Kuter, Katarzyna Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953228/
https://www.ncbi.nlm.nih.gov/pubmed/36830567
http://dx.doi.org/10.3390/biom13020197