Cargando…
GABA-A Alpha 2/3 but Not Alpha 1 Receptor Subunit Ligand Inhibits Harmaline and Pimozide-Induced Tremor in Rats
Treatment of tremors, such as in essential tremor (ET) and Parkinson’s disease (PD) is mostly ineffective. Exact tremor pathomechanisms are unknown and relevant animal models are missing. GABA-A receptor is a target for tremorolytic medications, but current non-selective drugs produce side effects a...
Autores principales: | Kosmowska, Barbara, Paleczna, Martyna, Biała, Dominika, Kadłuczka, Justyna, Wardas, Jadwiga, Witkin, Jeffrey M., Cook, James M., Sharmin, Dishary, Marcinkowska, Monika, Kuter, Katarzyna Z. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953228/ https://www.ncbi.nlm.nih.gov/pubmed/36830567 http://dx.doi.org/10.3390/biom13020197 |
Ejemplares similares
-
Pramipexole Reduces zif-268 mRNA Expression in Brain Structures involved in the Generation of Harmaline-Induced Tremor
por: Kosmowska, Barbara, et al.
Publicado: (2020) -
The Pathophysiology and Treatment of Essential Tremor: The Role of Adenosine and Dopamine Receptors in Animal Models
por: Kosmowska, Barbara, et al.
Publicado: (2021) -
Beyond the GFAP-Astrocyte Protein Markers in the Brain
por: Jurga, Agnieszka M., et al.
Publicado: (2021) -
Suppression of Harmaline Tremor by Activation of an Extrasynaptic GABA(A) Receptor: Implications for Essential Tremor
por: Handforth, Adrian, et al.
Publicado: (2018) -
Lesion of the Cerebellar Noradrenergic Innervation Enhances the Harmaline-Induced Tremor in Rats
por: Kolasiewicz, Wacław, et al.
Publicado: (2011)