Horse-Derived Ceramide Accentuates Glucosylceramide Synthase and Ceramide Synthase 3 by Activating PPARβ/δ and/or PPARγ to Stimulate Ceramide Synthesis

Horse-derived ceramide (HC), which contains galactosylceramides as its main component, significantly improves skin symptoms when applied topically to patients with atopic dermatitis. We speculated that efficacy resulted from the amelioration of epidermal ceramide metabolism, and we characterized tho...

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Detalles Bibliográficos
Autores principales: Igarashi, Tami, Yanagi, Hiroki, Yagi, Masayuki, Ichihashi, Masamitsu, Imokawa, Genji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953238/
https://www.ncbi.nlm.nih.gov/pubmed/36831084
http://dx.doi.org/10.3390/biomedicines11020548

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953238/
https://www.ncbi.nlm.nih.gov/pubmed/36831084
http://dx.doi.org/10.3390/biomedicines11020548

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