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In Vivo Acute Toxicity Studies of Novel Anti-Melanoma Compounds Downregulators of hnRNPH1/H2

Despite the recent advances in melanoma therapy, the need for new targets and novel approaches to therapy is urgent. We previously reported melanoma actives that work via binding and downregulating spliceosomal proteins hnRNPH1 and H2. Given the lack of knowledge about the side effects of using spli...

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Detalles Bibliográficos
Autores principales: Velayutham, Sadeeshkumar, Seal, Trisha, Danthurthy, Samaya, Zaias, Julia, Smalley, Keiran S. M., Minond, Dmitriy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953269/
https://www.ncbi.nlm.nih.gov/pubmed/36830718
http://dx.doi.org/10.3390/biom13020349