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CRISPR/Cas9-Induced Knockout of Sting Increases Susceptibility of Zebrafish to Bacterial Infection

Stimulator of interferon genes (STING) is an adapter protein that is activated when cyclic dinucleotides (CDNs) are present. CDNs originate from the cytosolic DNA of both pathogens and hosts. STING activation promotes efficient immune responses against viral infections; however, its impact in bacter...

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Detalles Bibliográficos
Autores principales: Sellaththurai, Sarithaa, Jung, Sumi, Kim, Myoung-Jin, Nadarajapillai, Kishanthini, Ganeshalingam, Subothini, Jeong, Joon Bum, Lee, Jehee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953276/
https://www.ncbi.nlm.nih.gov/pubmed/36830693
http://dx.doi.org/10.3390/biom13020324