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Cholesterol and Sphingomyelin Polarize at the Leading Edge of Migrating Myoblasts and Involve Their Clustering in Submicrometric Domains

Myoblast migration is crucial for myogenesis and muscular tissue homeostasis. However, its spatiotemporal control remains elusive. Here, we explored the involvement of plasma membrane cholesterol and sphingolipids in this process. In resting C2C12 mouse myoblasts, those lipids clustered in sphingomy...

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Detalles Bibliográficos
Autores principales: Vanderroost, Juliette, Avalosse, Noémie, Mohammed, Danahe, Hoffmann, Delia, Henriet, Patrick, Pierreux, Christophe E., Alsteens, David, Tyteca, Donatienne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953279/
https://www.ncbi.nlm.nih.gov/pubmed/36830688
http://dx.doi.org/10.3390/biom13020319