The Anti-Epileptic Drugs Lamotrigine and Valproic Acid Reduce the Cardiac Sodium Current

Anti-epileptic drugs (AEDs) are associated with increased risk of sudden cardiac death. To establish whether gabapentin, lamotrigine, levetiracetam, pregabalin, and valproic acid reduce the Na(v)1.5 current, we conducted whole-cell patch-clamp studies to study the effects of the five AEDs on current...

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Detalles Bibliográficos
Autores principales: Jia, Lixia, Verkerk, Arie O., Tan, Hanno L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953282/
https://www.ncbi.nlm.nih.gov/pubmed/36831014
http://dx.doi.org/10.3390/biomedicines11020477

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953282/
https://www.ncbi.nlm.nih.gov/pubmed/36831014
http://dx.doi.org/10.3390/biomedicines11020477

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