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The Anti-Epileptic Drugs Lamotrigine and Valproic Acid Reduce the Cardiac Sodium Current
Anti-epileptic drugs (AEDs) are associated with increased risk of sudden cardiac death. To establish whether gabapentin, lamotrigine, levetiracetam, pregabalin, and valproic acid reduce the Na(v)1.5 current, we conducted whole-cell patch-clamp studies to study the effects of the five AEDs on current...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953282/ https://www.ncbi.nlm.nih.gov/pubmed/36831014 http://dx.doi.org/10.3390/biomedicines11020477 |