Multiplexing AAV Serotype-Specific Neutralizing Antibodies in Preclinical Animal Models and Humans

The accurate assessment of AAV-specific pre-existing humoral immunity due to natural viral infection is critical for the efficient use of clinical gene therapy. The method described in the present study applies equivalent infection conditions to each AAV serotype (AAV1, AAV2, AAV3, AAV5, AAV6, AAV7,...

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Detalles Bibliográficos
Autores principales: Kuoch, Hisae, Krotova, Karina, Graham, Melanie L., Brantly, Mark L., Aslanidi, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953293/
https://www.ncbi.nlm.nih.gov/pubmed/36831059
http://dx.doi.org/10.3390/biomedicines11020523

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953293/
https://www.ncbi.nlm.nih.gov/pubmed/36831059
http://dx.doi.org/10.3390/biomedicines11020523

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