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Multiplexing AAV Serotype-Specific Neutralizing Antibodies in Preclinical Animal Models and Humans
The accurate assessment of AAV-specific pre-existing humoral immunity due to natural viral infection is critical for the efficient use of clinical gene therapy. The method described in the present study applies equivalent infection conditions to each AAV serotype (AAV1, AAV2, AAV3, AAV5, AAV6, AAV7,...
Autores principales: | Kuoch, Hisae, Krotova, Karina, Graham, Melanie L., Brantly, Mark L., Aslanidi, George |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953293/ https://www.ncbi.nlm.nih.gov/pubmed/36831059 http://dx.doi.org/10.3390/biomedicines11020523 |
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